ela-32(human) — TargetMol Chemicals

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Search Results for " ela-32(human) "

Compounds

Cat No.	Product Name	Synonyms	Targets
TP2097	ELA-32(human)	ELA-32 (human)
	Potent, high affinity apelin receptor agonist (IC50 = 0.27 nM; Kd = 0.51 nM). Exhibits no binding GPR15 and GPR25. Activates the PI3K/AKT pathway and promotes self-renewal of hESCs via cell-cycle progression and protein ...
TP1922L1	ELA-11 (human) acetate(1784687-32-6 free base)		Apelin receptor , Arrestin
	ELA-11 (human) acetate high affinity apelin receptor agonist (Ki = 14 nM). Bioactive fragment of ELA-32. Inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro.		Apelin receptor , Arrestin
T76052	ELA-32(human) TFA
	ELA-32(human) TFA is a potent apelin receptor agonist with high affinity, demonstrating an IC50 of 0.27 nM and a Kd of 0.51 nM. This compound does not bind to GPR15 or GPR25. It activates the PI3K/AKT signaling pathway, ...
TP1923	Elabela(19-32)	ELA-14 (human)
	Potent apelin (APJ) receptor agonist (Ki = 0.93 nM). Bioactive fragment of ELA-32. Activates Gαi1 pathway and β-arrestin-2 recruitment. Reduces arterial pressure in rat hearts. Active in vivo.
T76053	ELA-11(human) TFA
	ELA-11(human) TFA, a bioactive fragment of ELA-32, acts as a high-affinity apelin receptor agonist (K i =14 nM). It effectively inhibits forskolin-induced cAMP production and promotes β-arrestin recruitment in vitro, hig...