egfr/cdk2-in-2 — TargetMol Chemicals

Search Result

Search Results for " egfr/cdk2-in-2 "

Compounds

Cat No.	Product Name	Targets
T79727	EGFR/CDK2-IN-2	EGFR
	EGFR/CDK2-IN-2 (compound 6a) serves as a dual inhibitor targeting both EGFR and CDK-2, exhibiting IC50 values of 19.6 nM and 87.9 nM, respectively. It promotes apoptosis in MCF-7 cells and halts cell cycle progression du...	EGFR
T79729	EGFR/CDK2-IN-4	EGFR
	EGFR/CDK2-IN-4 (compound 4c) is a dual inhibitor targeting EGFR and CDK-2, demonstrating IC50 values of 89.6 nM for EGFR and 165.4 nM for CDK-2. It prompts apoptosis in MCF-7 cells and causes S phase cell cycle arrest, e...	EGFR
T79728	EGFR/CDK2-IN-3	EGFR
	EGFR/CDK2-IN-3 (compound 4b) serves as a dual inhibitor targeting both EGFR and CDK-2, exhibiting IC50 values of 71.7 nM and 113.7 nM, respectively. It prompts apoptosis in MCF-7 cells and halts the cell cycle in the S p...	EGFR
T81739	Multi-target kinase inhibitor 2	EGFR
	Compound 5K (Multi-target kinase inhibitor 2) is a multi-targeted kinase inhibitor demonstrating activity against EGFR, Her2, VEGFR2, and CDK2 with IC50 values between 40 to 204 nM. It exhibits cytotoxic effects on HepG2...	EGFR