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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3506 | Nazartinib | EGF816,NVS-816 | EGFR |
Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity... | |||
T11156L | Nazartinib mesylate | EGF816 (mesylate) | Others |
Nazartinib mesylate is a novel, covalent mutant-selective inhibitor of EGFR (Ki and Kinact: 31 nM and 0.222/min on EGFR(L858R/790M) mutant). | |||
T11156 | Nazartinib S-enantiomer | EGF816 (S-enantiomer) | Others |
Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib. |