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Cat No. | Product Name | Synonyms | Targets |
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T61390 | D18 | ||
D18 is an immune modulator that acts as a dual agonist for TLR7/8 (with EC50 values of 24 nM for hTLR7 and 10 nM for hTLR8, respectively). It enhances the expression of PD-L1 through epigenetic regulation, thereby increa... | |||
T37563 | C22 Ceramide (d18:1/22:0) | Cer(d18:1/22:0),C22 Ceramide,Ceramide (d18:1/22:0) | |
C22 Ceramide (d18:1/22:0) (C22 Ceramide), a long-chain ceramide containing behenic acid, is an endogenous bioactive sphingolipid.C22-Ceramide specifically inhibits MCSR and reduces C16 ceramide channel formation in isola... | |||
T35803 | C14 Ceramide (d18:1/14:0) | Cer(d18:1/14:0),N-Myristoyl-D-sphingosine | |
C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's research. | |||
T35805 | C16 Sphingomyelin (d18:1/16:0) | Sphingomyelin 16:0,N-Palmitoyl-D-sphingomyelin | Endogenous Metabolite |
C16 Sphingomyelin (d18:1/16:0) (N-Palmitoyl-D-sphingomyelin) is a phospholipid analog of phospholipid bilayer membranes, which can be used to study biofilm activity. | |||
T11891 | Lumefantrine-d18 | Benflumetol D18,Lumefantrine D18 | Others |
Lumefantrine D18 is an antimalarial drug, and is the deuterium labeled Lumefantrine. | |||
T38354 | Lactosylsphingosine (d18:1) | Lactosylsphingosine (d18:1) | |
Lactosylsphingosine is a bioactive sphingolipid and a form of lactosylceramide that is lacking the fatty acyl group. Lyso-lactosylceramide (1-50 μM) reduces viability of human neutrophils in a concentration-dependent man... | |||
T37291 | Lyso-Globotriaosylceramide (d18:1) | Lyso-Globotriaosylceramide (d18:1) | |
Lyso-globotriaosylceramide is a form of globotriaosylceramide that is lacking the fatty acyl group. It binds to Shiga toxin 1 (Stx1) in the presence of cholesterol and phosphatidylcholine but does not bind Stx2. It also ... | |||
T37010 | D-threo Sphinganine (d18:0) | D-threo Sphinganine (d18:0) | |
D-threo Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and L-erythro sphinganine (d18:0) . It induces autophagy in HCT116 cells when used at a concentration of 12 μM. D-... | |||
T37872 | C16 Galactosylceramide (d18:1/16:0) | C16 Galactosylceramide (d18:1/16:0) | |
C16 Galactosylceramide is a glycosphingolipid that contains a galactose moiety attached to a ceramide acylated with palmitic acid . | |||
T36323 | C8 Galactosylceramide (d18:1/8:0) | C8 Galactosylceramide (d18:1/8:0) | |
C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids. It increases the amount delivered and toxicity of doxorubicin in cancerous but not non-cancerous cells w... | |||
T37438 | C17 Globotriaosylceramide (d18:1/17:0) | C17 Globotriaosylceramide (d18:1/17:0) | |
C17 Globotriaosylceramide is a sphingolipid that has been used as an internal standard for the quantification of globotriaosylceramides in plasma and urine from patients with Fabry disease by GC-MS. | |||
T37564 | C4 Ceramide (d18:1/4:0) | C4 Ceramide (d18:1/4:0),Cer(d18:1/4:0) | |
C4 Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. [1] [2] [3] It inhibits IL-4 production by 16% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used... | |||
T35873 | C19 Ceramide (d18:1/19:0) | C19 Ceramide (d18:1/19:0) | |
C19 Ceramide is a naturally occurring ceramide that has been found in J. juncea extracts as well as rat brain and mouse heart.[1],[2],[3] It is elevated in adult and decreased in juvenile whole rat brain extracts by 114 ... | |||
T38286 | C26 Sphingomyelin (d18:1/26:0) | C26 Sphingomyelin (d18:1/26:0) | |
C26 Sphingomyelin is a sphingolipid that has been found in serum and cell or brain extracts.1,2,3C26 sphingomyelin levels are increased in the serum of patients with hemophagocytic lymphohistiocytosis, an inflammatory co... | |||
T36140 | BODIPY-C12 Ceramide (d18:1/12:0) | BODIPY-C12 Ceramide (d18:1/12:0) | |
BODIPY-C12 Ceramide (B12Cer) is a fluorescently-tagged form of C12 ceramide, with excitation/emission maxima at 505/540 nm, respectively. It is a fluorescently-labeled sphingolipid and has been utilized for quantifying a... | |||
T36987 | N,N-dimethyl Sphinganine (d18:0) | N,N-dimethyl Sphinganine (d18:0) | |
N,N-dimethyl Sphinganine (d18:0) is a sphingolipid that increases during development ofL. donovanipromastigotes.1 1.Silva, A.M., Cordeiro-da-Silva, A., and Coombs, G.H.Metabolic variation during development in culture of... | |||
T38452 | L-threo Lysosphingomyelin (d18:1) | L-threo-Sphingosylphosphorylcholine,L-threo Lysosphingomyelin (d18:1) | |
L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) is a naturally occurring bioactive sphingolipid. It acts as a potent agonist for S1P receptors, with EC50 values of 19.3, 131.8, and 313.3 nM for hS... | |||
T36860 | C22 Sphingomyelin (d18:1/22:0) | C22 Sphingomyelin (d18:1/22:0) | |
C22 Sphingomyelin is a naturally occurring form of sphingomyelin . Plasma levels of C22 sphingomyelin positively correlate with hepatic steatosis severity in patients with chronic hepatitis C virus (HCV). C22 Sphingomyel... | |||
T38182 | C17 Sphingomyelin (d18:1/17:0) | C17 Sphingomyelin (d18:1/17:0) | |
C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin. | |||
T36859 | C16 Globotriaosylceramide (d18:1/16:0) | C16 Globotriaosylceramide (d18:1/16:0) | |
C16 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from C16 lactosylceramide . C16 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raj... |