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Search Result

Search Results for " cdc7-in-1 "

15

Compounds

Cat No. Product Name Synonyms Targets
T10724 Cdc7-IN-1 CDK
Cdc7-IN-1 is a highly selective and ATP competitive inhibitor of Cdc7 kinase (IC50: 0.6 nM at 1 mM ATP). It potently inhibits Cdc7 activity in cancer cells and effectively induces cell death.
T9064 LY3143921 hydrate CDK
LY3143921 ((S)-Example 2) hydrate is an orally active CDC7 kinase inhibitor with broad in vitro anticancer activity [1].
T61224 Cdc7-IN-8
Cdc7-IN-8, a potent inhibitor, targets Cdc7, a serine/threonine kinase responsible for activating MCM promotion through phosphorylation of the microchromosome maintenance protein (MCM protein). MCM protein, an essential ...
T62230 Cdc7-IN-10
Cdc7-IN-10 is a potent inhibitor of Cdc7 (IC50 ≤ 1 nM) and can be used in studies of proliferative diseases.
T60815 Cdc7-IN-9
Cdc7-IN-9 can be used for the research of cancer which is a potent inhibitor of Cdc7 [1].
T62231 Cdc7-IN-11
Cdc7-IN-11 is a potent inhibitor of Cdc7 (IC50 ≤ 1 nM) and can be used in the study of proliferative diseases.
T60427 Cdc7-IN-15
Cdc7-IN-15 (Example 108) is an inhibitor of cdc7 kinase that has potential to be used for cancer research [1].
T61223 Cdc7-IN-19
Cdc7-IN-19 (compound 1-1) is a potent CDC7 inhibitor with an IC 50 of 1.49 nM [1].
T61289 Cdc7-IN-14
Cdc7-IN-14 (compound 82) is a highly potent inhibitor of CDC7, demonstrating an IC50 value of less than 1 nM. This compound, Cdc7-IN-14, exhibits promising potential for cancer research [1].
T60659 Cdc7-IN-12
Cdc7-IN-12 (compound 1) is a potent inhibitor of CDC7 (IC 50 of <1 nM) that has the potential in the cancer research. Cdc7-IN-12 exhibits antiproliferative activities in COLO205 cells with IC 50 of 100-1000 nM [1].
T61288 Cdc7-IN-13
Cdc7-IN-13 (compound 84) is a highly potent CDC7 inhibitor, exhibiting an IC50 value of <1 nM. This compound holds promise for cancer research [1].
T61436 Cdc7-IN-18
Cdc7-IN-18 (compound 1-2) is a highly effective inhibitor of the CDC7 enzyme. It has an IC 50 value of 1.29 nM for the Cdc7/DBF4 enzyme. In addition, this compound exhibits strong antiproliferative activities, with an IC...
T60589 Cdc7-IN-17
Cdc7-IN-17 is a potent inhibitor of CDC7 with an IC 50 of <10 μM that can be used in cancer research [1].
T61435 (S)-Cdc7-IN-18
(S)-Cdc7-IN-18, a potent CDC7 inhibitor, effectively impedes the overactivation of MCM2, a crucial tumor cell marker, induced by huCdc7 overexpression. Consequently, it inhibits the aberrant proliferation of tumor cells....
T60747 LY3143921
LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].
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