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Search Result

Search Results for " cbl-b-in-1 "

11

Compounds

Cat No. Product Name Synonyms Targets
T37356 Cbl-b-IN-1 Others
Cbl-b-IN-1 is a potent Cbl-b inhibitor (IC50 <100 nM) with potential anticancer activity for the study of intestinal inflammation.
T63790 Cbl-b-IN-3 E1/E2/E3 Enzyme
Cbl-b-IN-3 is a potent proto-oncogene-B (CPL-B) inhibitor of casitas B-series lymphoma (ic50 < 1 nM). Cpl-b, a cyclic E3 ubiquitin protein ligase, is involved in the setting of T lymphocyte activation thresholds. Cpl-b n...
T79895 Cbl-b-IN-8 E1/E2/E3 Enzyme
Cbl-b-IN-8 (Compound 293) is an inhibitor of both casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting half maximal inhibitory concentrations (IC50s) of 5.5 nM and 7.8 nM, respectively [1].
T79900 Cbl-b-IN-13 E1/E2/E3 Enzyme
Cbl-b-IN-13 (Example 520) is a potent Cbl-b inhibitor exhibiting an IC50 of less than 100 nM and is capable of activating T-cells [1].
T79897 Cbl-b-IN-10 E1/E2/E3 Enzyme
Cbl-b-IN-10 (Compound 463) is a potent inhibitor of both casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting half-maximal inhibitory concentrations (IC50s) of 6.0 nM and 3.5 nM, respectively [1].
T79899 Cbl-b-IN-12 E1/E2/E3 Enzyme
Cbl-b-IN-12 (Example 10) is an inhibitor of casitas B-lineage lymphoma-b (CBL-B), demonstrating a half-maximal inhibitory concentration (IC50) of less than 100 nM [1].
T79896 Cbl-b-IN-9 E1/E2/E3 Enzyme
Cbl-b-IN-9 (Compound 300) is an inhibitor targeting casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting potent inhibitory activity with half-maximal inhibitory concentrations (IC50s) of 5.6 nM and 4.7 nM, respecti...
T79893 Cbl-b-IN-6 E1/E2/E3 Enzyme
Cbl-b-IN-6 (Compound 246) is an inhibitor of both casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting inhibitory half-maximal inhibitory concentrations (IC50s) of 6.7 nM for Cbl-b and 5.2 nM for c-Cbl, respectivel...
T79894 Cbl-b-IN-7 E1/E2/E3 Enzyme
Cbl-b-IN-7 (Compound 248) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting inhibitory half-maximal inhibitory concentrations (IC50s) of 6.7 nM and 5.2 nM, respectively [1].
T79898 Cbl-b-IN-11 E1/E2/E3 Enzyme
Cbl-b-IN-11 (Compound 466) is an inhibitor of both casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, exhibiting half-maximal inhibitory concentrations (IC50s) of 6.4 nM and 6.1 nM, respectively [1].
T37468 Siamycin I
Siamycin I is a tricyclic peptide originally isolated from Streptomyces and has antiviral and antibacterial activities. It is active against laboratory strains and clinical isolates of HIV-1 (ED50s = 0.05-0.45 and 0.89-5...
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