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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10297L | AMG 487 | CXCR | |
AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively. | |||
T70411 | PS372424 HCl | ||
PS372424 is a specific agonist of human CXCR3. It has been shown to induce phosphorylation of ERK and block CXCL11 induced migration of CD45+ cells to air pouches generated on humanized mice. | |||
T73148 | ACT-777991 | ||
ACT-777991 is an orally active, selective CXCR3 antagonist with demonstrated stability in microsomes and hepatocytes across various animal models. This compound effectively inhibits the migration of activated T cells tow... | |||
T62325 | CXCR7 antagonist-1 hydrochloride | ||
CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of SDF-1 chemokine (also known as CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. hydrochloride can be u... | |||
T36982 | CXCR3 Antagonist 6c | ||
CXCR3 antagonist 6c is an antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3).1It inhibits calcium mobilization induced by chemokine (C-X-C motif) ligand 11 (CXCL11) in HEK293 cells expressing the human receptor (IC... |