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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T79654 | CRM1-IN-1 | CRM1 | |
CRM1-IN-1 (Compound KL1), a noncovalent inhibitor of CRM1, promotes nuclear degradation of CRM1 with an IC50 of 0.27 μM, inhibits CRM1-mediated nuclear export, suppresses cell proliferation, and induces apoptosis in colo... | |||
T79655 | CRM1-IN-2 | CRM1 | |
CRM1-IN-2 (Compound KL2) is a noncovalent inhibitor that targets CRM1, localizing it to the nuclear periphery, depleting its nuclear presence, and inhibiting its nuclear export function. It demonstrates the capability to... | |||
T60416 | CRM1 degrader 1 | ||
CRM1 degrader 1 (1l) is a low-toxic CRM1 degrader that induces apoptosis in gastric carcinoma and selectively inhibits the proliferation of gastric cancer[1]. |