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Search Results for " cgrp-i "

2

Compounds

5

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T21558 MK-3207
MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC 50 = 0.12 nM; K i = 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3. IC50 Value: 0.024 nM (Ki, Human CGRP) [1] As other CGRP recep...
T6590 MK-3207 Hydrochloride MK-3207 HCl CGRP Receptor
MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPK-00678 CALCA/CGRP Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Specific fragments of methylation changes in the target gene (Calca) were identified by IGV analysis. CGRP was applied to compare the effects on ASCs-T2DM morphology via phalloidin staining, proliferation through CCK-8 a...
TMPY-04120 Procalcitonin/CALCA Protein, Human, Recombinant (mFc) Human HEK293 Cells
Procalcitonin/CALCA Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 39.2 kDa and the accession number is P01258-1.
TMPY-00066 Procalcitonin/CALCA Protein, Human, Recombinant (His) Human HEK293 Cells
Procalcitonin/CALCA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.2 kDa and the accession number is P01258-1.
TMPH-01025 CALCA Protein, Human, Recombinant (GST) Human E. coli
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevate...
TMPY-03280 RAMP3 Protein, Human, Recombinant (hFc) Human HEK293 Cells
RAMP3 belongs to the RAMP family. Members of this family are single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs have a wide biological distribution; high concent...
TargetMol