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Cat No. | Product Name | Synonyms | Targets |
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T21558 | MK-3207 | ||
MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC 50 = 0.12 nM; K i = 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3. IC50 Value: 0.024 nM (Ki, Human CGRP) [1] As other CGRP recep... | |||
T6590 | MK-3207 Hydrochloride | MK-3207 HCl | CGRP Receptor |
MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2. |
Cat No. | Product Name | Species | Expression System |
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TMPK-00678 | CALCA/CGRP Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Specific fragments of methylation changes in the target gene (Calca) were identified by IGV analysis. CGRP was applied to compare the effects on ASCs-T2DM morphology via phalloidin staining, proliferation through CCK-8 a... | |||
TMPY-04120 | Procalcitonin/CALCA Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
Procalcitonin/CALCA Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 39.2 kDa and the accession number is P01258-1. | |||
TMPY-00066 | Procalcitonin/CALCA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Procalcitonin/CALCA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.2 kDa and the accession number is P01258-1. | |||
TMPH-01025 | CALCA Protein, Human, Recombinant (GST) | Human | E. coli |
CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevate... | |||
TMPY-03280 | RAMP3 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
RAMP3 belongs to the RAMP family. Members of this family are single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs have a wide biological distribution; high concent... |