cd73 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9210	CD73-IN-4		CD73
	CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor		CD73
T8875	CD73-IN-3	EX-A4254,LY-3475070	CD73
	CD73-IN-3 (LY-3475070) is a potent and selective CD73 inhibitor with an IC50 of 28 nM, and its use alone or in combination with pembrolizumab is currently being tested in patients with advanced cancer.		CD73
T40033	CD73-IN-5	CD73-IN-5
	CD73-IN-5 is a highly potent and selective small molecule inhibitor of CD73, demonstrating non-nucleotide characteristics. It exerts its inhibitory effects with a remarkable IC50 value of 19 nM.
T10721	CD73-IN-1		CD73
	CD73-IN-1 is a CD73 inhibitor with anticancer activity.		CD73
T61118	CD73-IN-12
	CD73-IN-12 is a highly effective CD73 inhibitor that displays strong potential in tumor suppression. CD73, an enzyme intricately linked to tumor development, angiogenesis, and metastasis, is significantly inhibited by CD...
T60779	CD73-IN-13
	CD73-IN-13 is able to be used in a medicament preparing for tumor-related diseases. CD73-IN-13 is a potent inhibitor of CD73 which is closely associated with tumor growth, angiogenesis and metastasis [1].
T61053	CD73-IN-11
	CD73-IN-11 is able to used for tumor-related diseases medicament preparing. CD73-IN-11 is an effective CD73 inhibitor. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP) whic...
T63128	CD73-IN-2
	CD73-IN-2 is a potent inhibitor of CD73 (IC50: 0.09 nM).
T61691	CD73-IN-6
	CD73-IN-6, serves as a potent inhibitor of CD73. This compound finds utility in cancer research [1].
T61090	CD73-IN-8
	CD73-IN-8, a potent CD73 inhibitor, prevents the catalytic activity of CD73, an enzyme responsible for converting extracellular 5'-phosphate adenosine (5'-AMP) to adenosine. Adenosine, once produced, can induce immunosup...
T61000	CD73-IN-10
	CD73-IN-10 can be used in preparing tumor-related diseases medicament. CD73-IN-10 is a potent CD73 inhibitor that can catalyze the adenosine production from extracellular 5'-phosphate adenosine (5'-AMP). Adenosine induce...
T60844	CD73-IN-9
	CD73-IN-9 is a potent CD73 inhibitor that be used in preparing the tumor-related diseases medicament. CD73 can catalyze the adenosine production from extracellular 5'-phosphate adenosine (5'-AMP). The adenosine can induc...
T60599	CD73-IN-7
	CD73-IN-7 is a potent CD73 inhibitor that can be used for preparing a medicament for tumor-related diseases. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP) which can indu...
T10216	AB-680		CD73
	AB-680 is a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity, displays >10,000-fold selectivity over related ectonucleotidases CD39.		CD73
T76735	Mupadolimab	CPI-006	CD73
	Mupadolimab (CPI-006) is a humanized FC-γR binding deficient IgG1 anti-CD73 antibody with potential anticancer activity and activation of CD73POS B cells.		CD73
T12569L	PSB-12379 ditriethylamine salt		CD73
	PSB-12379 ditriethylamine salt, a nucleotide analogue, is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human).		CD73
T22392	OP-5244		Others
	OP-5244 has comparable potency to bisphosphonic acid series and targets CD73.		Others
T12007	MethADP sodium salt		Others
	MethADP is a specific CD73 inhibitor.		Others
T12008	MethADP	Adenosine 5'-(α,β-methylene)diphosphate	Others
	MethADP is a specific inhibitor of CD73.		Others
T12569	PSB-12379		Others
	PSB-12379 is a potent inhibitor of Ecto-5'-Nucleotidase (CD73)(Kis of 9.03 nM (rat) and 2.21 nM (human)).		Others