3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7080 | CCT245737 | SRA737 | Chk |
CCT245737 (SRA737) is an orally active and selective Chk1 inhibitor (IC50: 1.3 nM); CCT245737 shows much less activity against Chk2 (IC50: 2440 nM). | |||
T70553 | CCT245737(S) | ||
CCT245737(S) is a highly selective oral checkpoint kinase 1 (CHK1) inhibitor. | |||
T70552 | Ipatasertib tosylate | ||
Ipatasertib, also known as GDC0068, is an orally active, potent and selective Akt inhibitor. GDC-0068 blocked Akt signaling both in cultured human cancer cell lines and in tumor xenograft models. Inhibition of Akt acti... |