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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5S0669 | Bergamottin | 5-Geranoxypsoralen,Bergamotine,Bergaptin | P450 |
1. Bergamottin (5-Geranoxypsoralen) can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in KK-Aydiabetic mice. | |||
T37810 | 6',7'-Epoxybergamottin | ||
6'7'-Epoxybergamottin is a furanocoumarin found in grapefruit. It is a potent inhibitor of the cytochrome P450 (CYP) isoform CYP3A4 with an IC50 value of 0.30 ppm in a cell-free assay, 0.33 μM in HL7 human liver cells, a... | |||
TN3146 | 6',7'-Dihydroxybergamottin acetonide | Others | |
6',7'-Dihydroxybergamottin is a potent inhibitor of CYP3A activity, and may be primarily responsible for the effects of grapefruit juice on cytochrome P450 activity in humans. | |||
TN3147 | 6',7'-Dihydroxybergamottin | P450 | |
6',7'-Dihydroxybergamottin(DHB), a well-known inhibitor of CYP3A4, the inhibition of CYP3A4 activity by DHB includes the inhibition of POR activity, DHB can inhibit nifedipine oxidation in a concentration-dependent manne... |