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Compounds

Cat No. Product Name Synonyms Targets
T6249 Avagacestat BMS-708163 Gamma-secretase
Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.
TargetMol