3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5058 | Pamiparib | BGB-290 | PARP |
Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor(IC50 of 0.9 nM and 0.5 nM for PARP1 and PARP2, respectively). It has potent PARP trapping, and capability to penetrate the brain, and can b... | |||
T28293 | Pamiparib maleate | BGB290,BGB 290,BGB-29 maleat 0 | |
Pamiparib is a highly potent and selective PARP inhibitor. BGB-290 selectively binds to PARP and prevents PARP-mediated repair of single-strand DNA breaks via the base-excision repair (BER) pathway. This enhances the acc... | |||
T71911 | CGP-11130 HCl | ||
4-Fluorophenibut (developmental code name CGP-11130; also known as β-(4-fluorophenyl)-γ-aminobutyric acid or β-(4-fluorophenyl)-GABA) is a GABAB receptor agonist which was never marketed. It is selective for the GABAB r... |