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20

Compounds

Cat No. Product Name Synonyms Targets
T2072 BET bromodomain inhibitor Epigenetic Reader Domain
BET bromodomain inhibitor is a potent BET inhibitor.
T10521 ODM-207 BET-IN-4,ODM207 Epigenetic Reader Domain
ODM-207 (BET-IN-4) is a potent BRD4 inhibitor.
T39374 PROTAC BET Degrader-10
PROTAC BET Degrader-10 (WO2017007612A1, example 37) is a highly efficient and selective small molecule compound designed to degrade BET protein BRD4. PROTAC BET Degrader-10 functions by utilizing specific ligands that co...
T39998 BET bromodomain inhibitor 1
BET bromodomain inhibitor 1 is an orally active, selective inhibitor of bromodomain and extra-terminal (BET) proteins. It specifically inhibits BRD4 with an IC50 of 2.6 nM. Additionally, BET bromodomain inhibitor 1 demon...
T10518 BET-BAY 002 Others
BET-BAY 002 is an effective BET inhibitor and exhibits efficacy in a multiple myeloma model.
T1906 Molibresib GSK 525762A,GSK525762,I-BET 762 Epigenetic Reader Domain
Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).
T10522 BET-IN-6 Epigenetic Reader Domain
BET-IN-6, a ligand with potent and high affinity for inhibiting BRD2/BRD4, plays a crucial role in the synthesis of PROTAC BRD2/BRD4 degrader-1 [1], targeting the protein BRD2/4.
T10520 BET-IN-2 Epigenetic Reader Domain
BET-IN-2 is a BET inhibitor (IC50: 52 nM for BRD4-BD1).
T12559 PROTAC BET degrader-2 Others
PROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins (IC50 of 9.6 nM ).
T13849 PROTAC BET Degrader-1 Epigenetic Reader Domain
PROTAC BET Degrader-1 is a potent degrader of BET based on PROTAC.
T13850 PROTAC BET degrader-3 Epigenetic Reader Domain
PROTAC BET Degrader-3 is a potent degrader OF BET based on PROTAC.
T10517 BET-BAY 002 (S enantiomer) Others
The S-enantiomer of BET-BAY 002, referred to as BET-BAY 002 S enantiomer, is a potent inhibitor of BET (Bromodomain and Extra-Terminal motif proteins).
T12557 PROTAC BET-binding moiety 1 Others
PROTAC BET-binding moiety 1 is a key intermediate in the synthesis of high affinity BET inhibitors
T12558 PROTAC BET-binding moiety 2 Others
PROTAC BET-binding moiety 2 is an BET bromodomain inhibitor.
T9619 I-BET567
I-BET567, a potent pan-BET inhibitor with oral activity, demonstrates pIC50 values of 6.9 and 7.2 for BRD4 BD1 and BD2, respectively. This compound has exhibited efficacy in mouse models of oncology and inflammation [1].
T62055 NVS-BET-1
NVS-BET-1 is a BET bromodomain inhibitor. NVS-BET-1 can regulate keratinocyte plasticity.
T61795 BET-IN-9
BET-IN-9 is a BET inhibitor[1].
T62275 BET-IN-8
BET-IN-8 (Compound 27) is a potent inhibitor of BET (Ki: 0.83 μM, Kd: 0.571 μM), which ameliorates LPS-induced sepsis in vivo.BET-IN-8 has shown potential in sepsis.
T2120 I-BET151 GSK1210151A Epigenetic Reader Domain
I-BET151 (GSK1210151A) (GSK1210151A) is a specific BET inhibitor for BRD2/3/4 (IC50: 0.5/0.25/0.79 μM, in cell-free assays).
T79610 BET-IN-17 Epigenetic Reader Domain
BET-IN-17, also known as compound 16, serves as a pan-inhibitor for BET, exhibiting inhibitory potencies (pIC50) of 7.8 for BET BD1 and 7.6 for BET BD2 [1].
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TargetMol