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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T23654 | Afeletecan free base | BAY 56-3722,BAY56-3722,BAY-563722,Afeletecan | |
Afeletecan is a water-soluble camptothecin derivative. Afeletecan stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. Both the initial cleavage reaction and religation steps ... | |||
T69862 | Afeletecan HCl | ||
Afeletecan, also known as BAY 56-3722, is a water-soluble camptothecin derivative conjugated to a carbohydrate moiety exhibiting antineoplastic activity. BAY 56-3722 stabilizes the topoisomerase I-DNA covalent complex a... |