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Search Results for " apixaban "

5

Compounds

Cat No. Product Name Synonyms Targets
T1736 Apixaban BMS-562247-01 Factor Xa
Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and pr...
T10349 Apixaban 13C,d3 Apixaban 13CD3,BMS-562247-01 13CD3 Others
Apixaban 13CD3 (BMS-562247-01 13CD3) is a deuterium-labeled Apixaban. Apixaban is a reversible inhibitor of Factor Xa (Ki: 0.08 nM and 0.17 nM in human and rabbit).
T19488 O-Desmethyl apixaban sulfate sodium O-Desmethyl apixaban sulfate sodium (503612-76-8 free base) Factor Xa
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.
T71429 O-Demethyl apixaban sulfate
O-Demethyl apixaban sulfate is a metabolite of Apixaban, a potent and highly selective factor Xa inhibitor. Apixaban is currently under development for treatment of arterial and venous thrombotic diseases.
T12279 O-Desmethyl apixaban Others
O-Desmethyl apixaban is a metabolite of Apixaban that is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively.
TargetMol