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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1736 | Apixaban | BMS-562247-01 | Factor Xa |
Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the conversion of prothrombin to thrombin and pr... | |||
T10349 | Apixaban 13C,d3 | Apixaban 13CD3,BMS-562247-01 13CD3 | Others |
Apixaban 13CD3 (BMS-562247-01 13CD3) is a deuterium-labeled Apixaban. Apixaban is a reversible inhibitor of Factor Xa (Ki: 0.08 nM and 0.17 nM in human and rabbit). | |||
T19488 | O-Desmethyl apixaban sulfate sodium | O-Desmethyl apixaban sulfate sodium (503612-76-8 free base) | Factor Xa |
O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans. | |||
T71429 | O-Demethyl apixaban sulfate | ||
O-Demethyl apixaban sulfate is a metabolite of Apixaban, a potent and highly selective factor Xa inhibitor. Apixaban is currently under development for treatment of arterial and venous thrombotic diseases. | |||
T12279 | O-Desmethyl apixaban | Others | |
O-Desmethyl apixaban is a metabolite of Apixaban that is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively. |