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Search Results for " afegostat "

6

Compounds

Cat No. Product Name Synonyms Targets
T19181 Afegostat D-Isofagomine,Isofagomine Others
Afegostat is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity.
T23653 Afegostat HCl Afegostat,AT-2101,Afegostat hydrochloride,AT2101
Afegostat is an acid β-glucosidase (GCase) active site inhibitor that acts as a pharmacological chaperone. Afegostat inhibits GCase with K(i) ~30 nM for wild-type and mutant enzymes. Afegostat was an experimental drug fo...
T72998 L-Afegostat 5-epi-Isofagomine
L-Afegostat (5-epi-Isofagomine), a glycosidase inhibitor and an iminosugar, is utilized in carbohydrate synthesis. It demonstrates β-Glucosidase inhibition with a Ki of 30 μM.
T19182 Afegostat D-Tartrate Isofagomine D-Tartrate,D-Isofagomine D-Tartrate Others
Afegostat D-Tartrate is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity.
T71476 Afegostat TFA
Afegostat, aslo known as Isofagomine, and AT2101, was an experimental drug for the treatment of certain forms of Gaucher's disease. Isofagomine (IFG) is an acid β-glucosidase (GCase) active site inhibitor that acts as a ...
T71474 H-201-70
H-201-70 is a partial beta1 agonist with adrenoreceptor stimulatory effects.
TargetMol