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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19181 | Afegostat | D-Isofagomine,Isofagomine | Others |
Afegostat is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity. | |||
T23653 | Afegostat HCl | Afegostat,AT-2101,Afegostat hydrochloride,AT2101 | |
Afegostat is an acid β-glucosidase (GCase) active site inhibitor that acts as a pharmacological chaperone. Afegostat inhibits GCase with K(i) ~30 nM for wild-type and mutant enzymes. Afegostat was an experimental drug fo... | |||
T72998 | L-Afegostat | 5-epi-Isofagomine | |
L-Afegostat (5-epi-Isofagomine), a glycosidase inhibitor and an iminosugar, is utilized in carbohydrate synthesis. It demonstrates β-Glucosidase inhibition with a Ki of 30 μM. | |||
T19182 | Afegostat D-Tartrate | Isofagomine D-Tartrate,D-Isofagomine D-Tartrate | Others |
Afegostat D-Tartrate is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity. | |||
T71476 | Afegostat TFA | ||
Afegostat, aslo known as Isofagomine, and AT2101, was an experimental drug for the treatment of certain forms of Gaucher's disease. Isofagomine (IFG) is an acid β-glucosidase (GCase) active site inhibitor that acts as a ... | |||
T71474 | H-201-70 | ||
H-201-70 is a partial beta1 agonist with adrenoreceptor stimulatory effects. |