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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2490 | Osimertinib | AZD-9291,Mereletinib | EGFR |
Osimertinib (AZD-9291) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib has antitumor activi... | |||
T3634 | Osimertinib mesylate | Mereletinib mesylate,AZD-9291 mesylate | EGFR |
Osimertinib mesylate (Mereletinib mesylate) is an irreversible and mutant selective EGFR inhibitor (IC50s: 12/1 nM for EGFR(L858R) and EGFR(L858R/T790M)). | |||
T10433 | Osimertinib dimesylate | Mereletinib (dimesylate),AZD-9291 (dimesylate) | EGFR |
Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M). | |||
T30268 | AZD9291-345 | AZD-9291345,AZD 9291345,AZD9291345 | |
AZD9291-345 is a compound which has a molecule weight 345, and structurally related to AZD9291. | |||
T2491 | AZ-5104 | EGFR | |
AZ5104 is a potent EGFR inhibitor. |