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Search Result

Search Results for " amy3 "

Targets

CGRP Receptor

5

Compounds

1

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6590 MK-3207 Hydrochloride MK-3207 HCl CGRP Receptor
MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2.
TP2078 AC 253
Amylin (AMY3) receptor antagonist. Inhibits andrenomedulin-stimulated cAMP production in vitro. Protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death ...
TP2135 CAC 253
Amylin (AMY3) antagonist (IC50 = 0.3 μM). Protects neuronal cells from Aβ(1-42)-induced cytotoxicity in vitro. Brain penetrant. Improves spatial memory and reduces Aβ plaque number and total area in a mouse Alzheimer's d...
T36555 Tyr-α-CGRP (human) (trifluoroacetate salt)
Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide . It binds to amylin receptors AMY1 and AMY3 in COS-7 cells expressing the human receptors (IC50s = 141 and 1.86 nM, respecti...
T21558 MK-3207
MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC 50 = 0.12 nM; K i = 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3. IC50 Value: 0.024 nM (Ki, Human CGRP) [1] As other CGRP recep...
Cat No. Product Name Synonyms Targets
TP1232L Amylin, amide, rat acetate(124447-81-0,free base) Amylin Receptor
Amylin, amide, rat acetate is a potent and high affinity ligand of AMY1 and AMY3 receptors and variably of AMY2 receptors.

Natural Products

Amylin, amide, rat acetate(124447-81-0,free base)
TP1232L
Synonym:
Target: Amylin Receptor

Recombinant Proteins

Species：
Human (2)
Expression System：
HEK293 Cells (2)
Tag：
C-His (1)
C-hFc (1)
Cat No. Product Name Species Expression System
TMPY-00340 Beta Amylase/AMY2B Protein, Human, Recombinant (hFc) Human HEK293 Cells
Beta Amylase/AMY2B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.4 kDa and the accession number is P19961-1.
TMPY-00503 Beta Amylase/AMY2B Protein, Human, Recombinant (His) Human HEK293 Cells
Beta Amylase/AMY2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.3 kDa and the accession number is P19961-1.
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