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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP2334 | PMX 53 acetate(219639-75-5 free base) | Complement System | |
PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an ag... | |||
T28429 | PMX-53 | PMX53,PMX 53 | |
PMX-53 is a Mas-related gene 2 (MrgX2) agonist and C5aR(CD88) antagonist. PMX-53 reduces atherosclerotic lesions in a mouse model of atherosclerosis, inhibits lung metastasis in a mouse breast cancer model, inhibits C5a-... |