2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11569 | HKI-357 | EGFR | |
HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2 (IC50s: 34 nM and 33 nM). HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation. | |||
T68360 | HKI-357 dimaleate | ||
HKI-357 dimaleate is an irreversible dual inhibitor of EGFR and ERBB2. HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation. |