7
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4923 | 7-Dehydrocholesterol | Provitamin D3,7-DHC | Endogenous Metabolite |
7-Dehydrocholesterol (Provitamin D3) down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts. | |||
T10167 | 5-Dehydroepisterol | Others | |
5-Dehydroepisterol is an episterol derivative with anti-fungal activities. It can be formed by C-5 sterol desaturase and converted into 24-methylenecholesterol by 7-dehydrocholesterol reductase. | |||
T71562 | Boxidine | ||
Boxidine inhibits the transformation of 7-dehydrocholesterol to cholesterol & also inhibits sterol absorption. | |||
T74208 | Pyrocholecalciferol | ||
Pyrocholecalciferol, a vitamin D analogue, is produced through the photochemical transformation of 7-dehydrocholesterol (7-DHC) [1] [2]. | |||
T70151 | MeTC7 | ||
MeTC7 is a VDR antagonist, which can be synthesized from 7-dehydrocholesterol (6) in two steps, inhibits VDR selectively, suppresses the viability of cancer cell-lines, and reduces the growth of the spontaneous transgen... | |||
T82853 | BM 15766 sulfate | ||
BM 15766 sulfate, an inhibitor of 7-dehydrocholesterol δ7-reductase, effectively reduces plasma cholesterol levels and functions as a hypolipidemic agent [1] [2]. | |||
T68219 | Peraclopone | ||
Peraclopone is a hypolidemic drug. It is an inhibitor of 7-Dehydrocholesterol reductase. Peraclopone potently inhibits the final step in cholesterol biosynthesis. Feeding this agent to rats leads to a rapid replacement o... |