3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10297L | AMG 487 | CXCR | |
AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively. | |||
T10297 | AMG 487 (S-enantiomer) | Others | |
AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist. | |||
T22477 | (±)-AMG 487 | Others | |
AMG 487 is an effective and selective antagonist of chemokine receptor 3. AMG 487 inhibited CXCR3-mediated cell migration induced by three CXCR3 chemokines, IP-10, ITAC and MIG (IC50: 8, 15 and 36 nM, respectively). |