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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T62916 | GEM144 | ||
GEM144 is a potent, orally active dual inhibitor of DNA polymerase α (POLA1) and HDAC 11. GEM144 induces p53 acetylation, activates p21, blocks the cell cycle in G1/S phase and induces apoptosis. |