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Search Results for " 1858211-28-5 "

3

Compounds

Cat No. Product Name Synonyms Targets
T70115 Pamiparib hydrate
Pamiparib, also known as BGB-290, is a highly potent and selective PARP inhibitor with favorable drug metabolism and pharmacokinetic properties. BGB-290 selectively binds to PARP and prevents PARP-mediated repair of sin...
T28293 Pamiparib maleate BGB290,BGB 290,BGB-29 maleat 0
Pamiparib is a highly potent and selective PARP inhibitor. BGB-290 selectively binds to PARP and prevents PARP-mediated repair of single-strand DNA breaks via the base-excision repair (BER) pathway. This enhances the acc...
T5058 Pamiparib BGB-290 PARP
Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor(IC50 of 0.9 nM and 0.5 nM for PARP1 and PARP2, respectively). It has potent PARP trapping, and capability to penetrate the brain, and can b...
TargetMol