2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19181 | Afegostat | D-Isofagomine,Isofagomine | Others |
Afegostat is a pharmacological chaperone that specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum with high affinity. | |||
T23653 | Afegostat HCl | Afegostat,AT-2101,Afegostat hydrochloride,AT2101 | |
Afegostat is an acid β-glucosidase (GCase) active site inhibitor that acts as a pharmacological chaperone. Afegostat inhibits GCase with K(i) ~30 nM for wild-type and mutant enzymes. Afegostat was an experimental drug fo... |