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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3209 | AMG-337 | AMG337 | c-Met/HGFR |
AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337(AMG337) inhibits MET kinase activity (IC50: < 5 nM). | |||
T70318 | AMG-337 monohydrate | ||
AMG-337 monohydrate is a highly selective small molecule MET inhibitor. Aberrant hepatocyte growth factor (HGF)/MET signaling has been implicated in hepatocarcinogenesis, suggesting that MET may serve as an attractive th... |