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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10859 | COH34 | 1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol | Others |
COH34 (1-[(E)-(4-methylphenyl)sulfanyliminomethyl]naphthalen-2-ol) is a selective inhibitor of PARG with an IC50 of 0.37 nM and a Kd of 0.547 μM. COH34 prolongs PARylation at DNA lesions and traps DNA repair factors. |