keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ω-Agatoxin IVA TFA is a potent selective inhibitor of P/Q type Ca2+ (Cav2.1) channels, exhibiting IC50 values of 2 nM for P-type and 90 nM for Q-type channels. It effectively inhibits glutamate exocytosis and calcium influx induced by high potassium, with IC50 ranging from 30 to 225 nM. Additionally, this compound blocks high potassium-induced serotonin and norepinephrine release, while having no impact on L-type or N-type calcium channels [1][2].
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Description | ω-Agatoxin IVA TFA is a potent selective inhibitor of P/Q type Ca2+ (Cav2.1) channels, exhibiting IC50 values of 2 nM for P-type and 90 nM for Q-type channels. It effectively inhibits glutamate exocytosis and calcium influx induced by high potassium, with IC50 ranging from 30 to 225 nM. Additionally, this compound blocks high potassium-induced serotonin and norepinephrine release, while having no impact on L-type or N-type calcium channels [1][2]. |
Molecular Weight | 5316.27 |
Formula | C217H360N68O60S10.C2HF3O2 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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ω-Agatoxin IVA TFA inhibitor inhibit