Powder: -20°C for 3 years | In solvent: -80°C for 1 year
m-PEG11-acid is a non-cleavable 11-unit polyethylene glycol (PEG) linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1]. It is similarly employed as a PEG-based linker for PROTAC synthesis [2].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 5 days | $ 37.00 | |
10 mg | 5 days | $ 51.00 |
Description | m-PEG11-acid is a non-cleavable 11-unit polyethylene glycol (PEG) linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1]. It is similarly employed as a PEG-based linker for PROTAC synthesis [2]. |
In vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Molecular Weight | 544.63 |
Formula | C24H48O13 |
CAS No. | 2280998-74-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
m-PEG11-acid 2280998-74-3 Others m PEG11 acid mPEG11acid m-PEG-11-acid inhibitor inhibit