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PDGF R beta/CD140b Protein, Canine, Recombinant (His)
(Synonyms: PDGFR-β, PDGFRB, PDGFR-2, PDGFR1, PDGFR, PDGF R β/CD140b, PDGF R β, PDGF R beta, JTK12, CD140B) Copy Product InfoSynonyms: PDGFR-β, PDGFRB, PDGFR-2, PDGFR1, PDGFR, PDGF R β/CD140b, PDGF R β, PDGF R beta, JTK12, CD140B
Catalog No. TMPK-01050 Copy Product Info
PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the accession number is Q6QNF3.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $58 | 7-10 days | 7-10 days | |
| 10 µg | $92 | 7-10 days | 7-10 days | |
| 20 µg | $148 | 7-10 days | 7-10 days | |
| 50 µg | $289 | 7-10 days | 7-10 days | |
| 100 µg | $487 | 7-10 days | 7-10 days | |
| 200 µg | $883 | 7-10 days | 7-10 days | |
| 500 µg | $1,950 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Human PDGFB, His Tag immobilized on CM5 Chip can bind Canine PDGF R beta, His Tag with an affinity constant of 0.203 μM as determined in SPR assay. |
| Description | PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the accession number is Q6QNF3. |
| Species | Canine |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | Q6QNF3 |
| Construction | Gly32-Val532 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | PDGFR-β, PDGFRB, PDGFR-2, PDGFR1, PDGFR, PDGF R β/CD140b, PDGF R β, PDGF R beta, JTK12, CD140B |
| Research Background | PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites. |
| Molecular Weight | 57.25 kDa (predicted). Due to glycosylation, the protein migrates to 70-100 kDa based on Tris-Bis PAGE result. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: PDGF R beta/CD140b Protein, Canine, Recombinant (His) chemical structure | PDGF R beta/CD140b Protein, Canine, Recombinant (His) molecular weight
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