Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GKI-1 HCl is a Greatwall (GWL) kinase inhibitor that inhibits hGWLFL and hGWL-KinDom.The inhibitory effect of GKI-1 HCl on ROCK1 is more significant.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 161.00 | |
5 mg | In stock | $ 393.00 | |
10 mg | In stock | $ 585.00 | |
25 mg | In stock | $ 937.00 | |
50 mg | In stock | $ 1,270.00 | |
100 mg | In stock | $ 1,690.00 | |
500 mg | In stock | $ 3,430.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 441.00 |
Description | GKI-1 HCl is a Greatwall (GWL) kinase inhibitor that inhibits hGWLFL and hGWL-KinDom.The inhibitory effect of GKI-1 HCl on ROCK1 is more significant. |
Targets&IC50 | GWL (human):4.9 µM, GWL-KinDom (human):4.9 µM |
In vitro | GKI-1 (25 and 50 µM, 0-8.5 h) reduces ENSA/ARPP19 phosphorylation levels in Hela cells, resulting in a decrease in mitotic events, mitotic arrest/cell death, and cytokinesis failure.[1] |
Synonyms | GKI-1 HCl( 2444764-03-6 Free base) |
Molecular Weight | 306.19 |
Formula | C15H13Cl2N3 |
CAS No. | T11402L |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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GKI-1 HCl T11402L Cell Cycle/Checkpoint Cytoskeletal Signaling Stem Cells ROCK 2444764-03-6 Free base 2444764-03-6 GKI-1 HCl( 2444764-03-6 Free base) inhibitor inhibit