Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ZK168281 is a 25-carboxylic ester 1α,25(OH)2D3 analog and a pure antagonist of VDR (Kd of 0.1 nM). ZK168281 is an effective inhibitor of the coactivator (CoA) interaction of its receptor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 3,470.00 | |
50 mg | 10-14 weeks | $ 4,580.00 | |
100 mg | 10-14 weeks | $ 6,400.00 |
Description | ZK168281 is a 25-carboxylic ester 1α,25(OH)2D3 analog and a pure antagonist of VDR (Kd of 0.1 nM). ZK168281 is an effective inhibitor of the coactivator (CoA) interaction of its receptor. |
Targets&IC50 | VDR:(kd)0.1 nM |
In vitro | ZK168281 resembles more the mouse constitutive androstane receptor (CAR) inverse agonist Androstanol in its ability to recruit corepressor (CoR) proteins. |
Molecular Weight | 510.7 |
Formula | C32H46O5 |
CAS No. | 186371-96-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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ZK168281 186371-96-0 Others ZK-168281 ZK 168281 inhibitor inhibit