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XP-59

XP-59
XP-59 is a potent the SARS-CoV Mpro inhibitor(Ki : 0.1 μM).
Catalog No. T8419Cas No. 890402-73-0
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Purity:100%
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XP-59

Catalog No. T8419Cas No. 890402-73-0
XP-59 is a potent the SARS-CoV Mpro inhibitor(Ki : 0.1 μM).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$31In Stock
5 mg$73In Stock
10 mg$119In Stock
25 mg$212In Stock
50 mg$323In Stock
100 mg$448In Stock
200 mg$633In Stock
1 mL x 10 mM (in DMSO)$80In Stock
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Product Introduction

Bioactivity
Description
XP-59 is a potent the SARS-CoV Mpro inhibitor(Ki : 0.1 μM).
Targets&IC50
Mpro (SARS CoV):0.1 μM(ki)
Chemical Properties
Molecular Weight282.3
FormulaC15H14N4O2
Cas No.890402-73-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 57.5 mg/mL (203.68 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5423 mL17.7117 mL35.4233 mL177.1165 mL
5 mM0.7085 mL3.5423 mL7.0847 mL35.4233 mL
10 mM0.3542 mL1.7712 mL3.5423 mL17.7117 mL
20 mM0.1771 mL0.8856 mL1.7712 mL8.8558 mL
50 mM0.0708 mL0.3542 mL0.7085 mL3.5423 mL
100 mM0.0354 mL0.1771 mL0.3542 mL1.7712 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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