Powder: -20°C for 3 years | In solvent: -80°C for 1 year
WZ4002-hydroxyl is a WZ4002 derivative or WZ4002 analogue in which methoxy is replaced by hydroxyl and can be detected in 50% of patients with clinical resistance to gefitinib or erlotinib. WZ4002 has a basic chemical skeleton (covalent pyrimidine) that differs from other EGFR inhibitors.
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Description | WZ4002-hydroxyl is a WZ4002 derivative or WZ4002 analogue in which methoxy is replaced by hydroxyl and can be detected in 50% of patients with clinical resistance to gefitinib or erlotinib. WZ4002 has a basic chemical skeleton (covalent pyrimidine) that differs from other EGFR inhibitors. |
Synonyms | WZ4002 analog, WZ4002 demethyl derivate, WZ 4002-hydroxy, WZ-4002-hydroxy |
Molecular Weight | 480.95 |
Formula | C24H25ClN6O3 |
CAS No. | T35147 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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WZ4002-hydroxy T35147 WZ4002 analog, WZ4002 demethyl derivate WZ 4002-hydroxy WZ4002 hydroxy WZ4002hydroxy WZ-4002-hydroxy inhibitor inhibit