Powder: -20°C for 3 years | In solvent: -80°C for 1 year
WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | WD2000-012547 is a selective inhibitor of poly(ADP-ribose)-polymerase (PARP-1) (pKi: 8.221). |
Targets&IC50 | PARP1:8.221 (pki) |
In vitro | Poly(ADP-ribose) polymerase-1 (PARP-1) operates as both a sensor and signal molecule for DNA damage, playing a crucial role in repairing DNA breaks caused by radiation and chemotherapy. Inhibiting this enzyme, as demonstrated by WD2000-012547—a PARP-1 inhibitor with a pKi of 8.221—holds promise for enhancing the effectiveness of cancer treatments through chemotherapy or radiotherapy. |
Molecular Weight | 262.31 |
Formula | C17H14N2O |
CAS No. | 283172-68-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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WD2000-012547 283172-68-9 Others WD2000 012547 WD2000012547 WD-2000-012547 inhibitor inhibit