Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 41.00 | |
2 mg | In stock | $ 58.00 | |
5 mg | In stock | $ 95.00 | |
10 mg | In stock | $ 138.00 | |
25 mg | In stock | $ 263.00 | |
50 mg | In stock | $ 459.00 | |
100 mg | In stock | $ 657.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 112.00 |
Description | VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM). |
Targets&IC50 | mGluR4:19.8 nM(EC50) |
In vivo | VU 0364439 possess less than ideal PK properties preventing their use as in vivo tools. It shows better stability in HLM (63% remaining) than RLM (2% remaining). [1] |
Molecular Weight | 422.29 |
Formula | C18H13Cl2N3O3S |
CAS No. | 1246086-78-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 79 mg/mL (187.1 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
VU 0364439 1246086-78-1 Neuroscience GluR Metabotropic glutamate receptors VU-0364439 VU0364439 Inhibitor mGluR inhibit inhibitor