Powder: -20°C for 3 years
In solvent: -80°C for 2 years
UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 μM.
Description | UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 μM. |
Targets&IC50 | EAAT1:0.66 μM. |
In vitro | A small but significant decrease in the total expression levels of both HA-EAAT1 and HA-GLAST is observed in cells preincubated with 100 μM UCPH-101 (p=0.048). UCPH-101 and UCPH-102 inhibit EAAT1 anion currents in a concentration-dependent manner, with KD values of 0.34±0.03 μM (Hill=1.3±0.13, n≥9) for UCPH-101 and 0.17±0.02 μM (Hill=0.97±0.11, n≥7) for UCPH-102. |
Synonyms | UCPH 101 |
Molecular Weight | 422.48 |
Formula | C27H22N2O3 |
CAS No. | 1118460-77-7 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 10.6 mg/mL(25 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
UCPH-101 1118460-77-7 Metabolism transporter UCPH 101 inhibit UCPH101 Inhibitor inhibitor