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TRAM 39

Catalog No. T23471 CAS 197525-99-8

Synonyms: 2-Chloro-alpha,alpha-diphenylbenzeneacetonitrile, TRAM-39, ZINC27105797, 2-(2-chlorophenyl)-2,2-diphenylacetonitrile

TRAM 39 (2-Chloro-α,α-diphenylbenzeneacetonitrile) is a selective blocker of intermediate-conductance Ca2+-activated K+channels.

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TRAM 39, CAS 197525-99-8

Pack Size	Availability	Price/USD
1 mg	In stock	$ 30.00
2 mg	In stock	$ 42.00
5 mg	In stock	$ 68.00
10 mg	In stock	$ 109.00
25 mg	In stock	$ 222.00
50 mg	In stock	$ 353.00
100 mg	In stock	$ 558.00
500 mg	In stock	$ 1,180.00

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Purity: 99.51%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	TRAM 39 (2-Chloro-α,α-diphenylbenzeneacetonitrile) is a selective blocker of intermediate-conductance Ca2+-activated K+channels.
In vitro	In coeliac neurons, TRAM 39 depressed the amplitude of the prolonged conductance underlying the slow afterhyperpolarization, (gKCa2) by 57%[1].

Synonyms	2-Chloro-alpha,alpha-diphenylbenzeneacetonitrile, TRAM-39, ZINC27105797, 2-(2-chlorophenyl)-2,2-diphenylacetonitrile
Molecular Weight	303.78
Formula	C20H14ClN
CAS No.	197525-99-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 15 mg/ml (49.4 mM)

References and Literature

1. Davies PJ, Thomas EA, Bornstein JC. Different types of potassium channels underlie the long afterhyperpolarization in guinea-pig sympathetic and enteric neurons. Auton Neurosci. 2006 Jan 30;124(1-2):26-30. 2. Weston AH, et al. Bradykinin-induced, endothelium-dependent responses in porcine coronary arteries: involvement of potassium channel activation and epoxyeicosatrienoic acids. Br J Pharmacol. 2005 Jul;145(6):775-84.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Bioactive Compound Library Bioactive Compounds Library Max Anti-Cancer Compound Library

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Keywords

TRAM 39 197525-99-8 Membrane transporter/Ion channel Potassium Channel 2-Chloro-a,a-diphenylbenzeneacetonitrile 2-Chloro-alpha,alpha-diphenylbenzeneacetonitrile 2-Chloro-α,α-diphenylbenzeneacetonitrile TRAM-39 ZINC27105797 TRAM39 ZINC 27105797 ZINC-27105797 2-(2-chlorophenyl)-2,2-diphenylacetonitrile inhibitor inhibit

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