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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21325 | TAK-441 | TAK441 | Hedgehog/Smoothened |
TAK-441 is an orally active inhibitor of Hedgehog signaling(IC50 = 4.4 nM) with potent antitumor activity. TAK-441 suppresses transcription factor Gli1 mRNA expression and tumor growth. |