Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Safotibant (LF-22-0542) is a bradykinin B1 receptor antagonist with anti-inflammatory and analgesic activity for the topical treatment of diabetic macular edema.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 146.00 | |
5 mg | In stock | $ 350.00 | |
10 mg | In stock | $ 530.00 | |
25 mg | In stock | $ 859.00 | |
50 mg | In stock | $ 1,180.00 | |
100 mg | In stock | $ 1,590.00 | |
500 mg | In stock | $ 3,190.00 |
Description | Safotibant (LF-22-0542) is a bradykinin B1 receptor antagonist with anti-inflammatory and analgesic activity for the topical treatment of diabetic macular edema. |
In vivo | LF22-0542 (1% in saline; eye drop; twice a day for 7 days; diabetic rats) significantly reduced Retinal plasma extravasation, leukostasis, and mRNA levels of B(1)R, iNOS, COX-2, VEGF receptor type 2, IL-1β and HIF-1α to the control value level.[1] |
Synonyms | LF220542, LF 220542, LF 22-0542, LF-220542, LF-22-0542, LF22-0542 |
Molecular Weight | 502.63 |
Formula | C25H34N4O5S |
CAS No. | 633698-99-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (99.48 mM)
You can also refer to dose conversion for different animals. More
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Safotibant 633698-99-4 GPCR/G Protein Bradykinin Receptor LF220542 LF 220542 LF 22-0542 LF-220542 LF-22-0542 LF22-0542 inhibitor inhibit