Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SMP-028 is a neutral cholesterol esterase (CEase) inhibitor(IC50 : 1.01 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | SMP-028 is a neutral cholesterol esterase (CEase) inhibitor(IC50 : 1.01 μM). |
Targets&IC50 | CEase:1.01 μM |
In vitro | SMP-028 potently and concentration-dependently inhibits neutral cholesterol esterase (CEase)(IC50: 1.01 μM). On the other hand, SMP-028 inhibitS other steroidogenic enzymes is weak with IC50 values>10 μM. In particular, SMP-028 does not inhibit acid CEase and only weakly reduces the activity of CYP11A1 with IC50 values>100 μM and 49.8 μM. respectively [1]. SMP-028 at 10 μM or less does not affect the viability of male adrenal cells, female adrenal cells, testicular cells, and ovarian cells. SMP-028 at concentrations higher than 30 μM significantly reduce the viability of male adrenal cells, female adrenal cells [2]. |
Molecular Weight | 455.55 |
Formula | C23H26FN5O2S |
CAS No. | 914389-14-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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SMP-028 914389-14-3 Others SMP 028 SMP028 inhibitor inhibit