Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SGK1-IN-1 is a highly active and selective SGK-1 inhibitor(IC50 of 1 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | 5 days | $ 233.00 | |
5 mg | 5 days | $ 297.00 | |
25 mg | 6-8 weeks | $ 987.00 | |
50 mg | 6-8 weeks | $ 1,360.00 | |
100 mg | 6-8 weeks | $ 1,860.00 |
Description | SGK1-IN-1 is a highly active and selective SGK-1 inhibitor(IC50 of 1 nM). |
Targets&IC50 | SGK1:1 nM |
In vitro | SGK1-IN-1 (14n) demonstrates favorable SGK isoform selectivity, exhibiting potent activity towards hSGK2 and moderate activity against hSGK3, with IC50 values of 1 and 41 nM at ATP concentrations of 10 μM and 50 μM, respectively. Additionally, it shows cellular efficacy by inducing SGK1-dependent phosphorylation of GSK3β in U2OS cells, achieving an activity level of 0.69 μM[2]. |
Molecular Weight | 418.83 |
Formula | C17H12ClFN6O2S |
CAS No. | 1279829-87-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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SGK1-IN-1 1279829-87-6 Others SGK1IN1 SGK1 IN 1 SGK-1-IN-1 inhibitor inhibit