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Risperidone E-oxime

Catalog No. T12734 CAS 691007-09-7

Risperidone E-oxime is an impurity of Risperidone. Risperidone is a serotonin blocker of 5-HT2 receptor, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist(Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively ).

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Risperidone E-oxime, CAS 691007-09-7

Pack Size	Availability	Price/USD	Quantity
1 mg	35 days	$ 288.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	430.49
Formula	C23H28F2N4O2
CAS No.	691007-09-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Pavel Slanina, et al. Process for making risperidone and intermediates therefor. US20040097523A1. 2. Nyberg S, et al. 5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone. Psychopharmacology (Berl). 1993;110(3):265-72. 3. Zhu HJ, et al. Risperidone and paliperidone inhibit p-glycoprotein activity in vitro. Neuropsychopharmacology. 2007 Apr;32(4):757-64.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Risperidone E-oxime 691007-09-7 Others Risperidone Eoxime Risperidone E oxime inhibitor inhibit

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