Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RP-001 hydrochloride is a selective agonist of picomolar short-acting S1P1 (EDG1)(EC50 of 9 pM), has little activity on S1P2-S1P4 and only moderate affinity for S1P5.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 93.00 | |
5 mg | 35 days | $ 394.00 | |
10 mg | 35 days | $ 623.00 | |
25 mg | 35 days | $ 1,320.00 |
Description | RP-001 hydrochloride is a selective agonist of picomolar short-acting S1P1 (EDG1)(EC50 of 9 pM), has little activity on S1P2-S1P4 and only moderate affinity for S1P5. |
In vitro | Dose-dependent lymphopenia of CD4+ T cells elicited by RP-001 hydrochloride. RP-001 hydrochloride induces acute lymphopenia with rapid recovery to untreated levels. |
In vivo | Dose-dependent rapid lymphopenia caused by RP-001 hydrochloride(EC50 of 0.03 mg/kg). |
Molecular Weight | 468.93 |
Formula | C24H25ClN4O4 |
CAS No. | 1781880-34-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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RP-001 hydrochloride 1781880-34-9 Others RP001 hydrochloride RP 001 hydrochloride RP 001 Hydrochloride RP-001 Hydrochloride RP001 Hydrochloride inhibitor inhibit