Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RMI 10874 is a tilorone analogue. Tilorone is an orally bioavailable antiviral agent.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | RMI 10874 is a tilorone analogue. Tilorone is an orally bioavailable antiviral agent. |
In vivo | Pre-treatment of BALB/c mice with the RMI 10,874DA completely eliminates lung colonization of an H-2-negative (GR9.B9) MCA-induced fibrosarcoma clone in an experimental metastasis assay. The effect of a tilorone analogue (RMI 10,874DA) and anti-asialo GM1 serum is studied on the survival of BALB/c and C57B1/6 mice after i.v. injections of different syngeneic murine tumor cells. Natural killer (NK) cell activation in vivo by RMI 10874 prolongs survival and inhibits metastasis formation in mice, even when pretreatment consists of a single dose of the analogue[2]. Tilorone is a small-molecule, orally bioavailable drug that is used clinically as an antiviral[3]. |
Molecular Weight | 370.44 |
Formula | C21H26N2O4 |
CAS No. | 38020-45-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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RMI 10874 38020-45-0 Others RMI-10874 RMI10874 inhibitor inhibit