keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Quinupristin-Dalfopristin Complex is a mixture of two streptogramin antibiotics. Quinupristin-dalfopristin complex is a mixture of two streptogramin antibiotics, dalfopristin, and quinupristin. Streptogramin antibiotics are divided into types A and B, which in combination can act synergistically.
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Description | Quinupristin-Dalfopristin Complex is a mixture of two streptogramin antibiotics. Quinupristin-dalfopristin complex is a mixture of two streptogramin antibiotics, dalfopristin, and quinupristin. Streptogramin antibiotics are divided into types A and B, which in combination can act synergistically. |
In vitro | In vitro: A previous study compared the molecular interactions of the streptogramin combinations Synercid (type A, dalfopristin; type B, quinupristin) and NXL 103 (type A, flopristin; type B, linopristin) with the Escherichia coli 70S ribosome. Results showed that the streptogramin A and B components in Synercid and NXL 103 exhibited synergistic antimicrobial activity against certain pathogenic bacteria. Moreover, in transcription-coupled translation assays, only combinations including dalfopristin, the streptogramin A component of Synercid, showed synergy [1]. |
In vivo | In vivo: A previous animal study aimed to investigate the efficacy of quinupristin/dalfopristin in the prevention of prosthetic graft infection in a rat subcutaneous pouch model. Results showed that quinupristin/dalfopristin had significantly higher efficacy than levofloxacin and doxycycline. In addition, only the group treated with quinupristin/dalfopristin combined with levofloxacin or doxycycline showed no evidence of staphylococcal infection [2]. |
Molecular Weight | 1905.3 |
Formula | C34H51N4O9S[CH3SO3]·C53H68N9O10S[CH3SO3] |
CAS No. | TP2285 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
Ethanol: Soluble
You can also refer to dose conversion for different animals. More
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Quinupristin-Dalfopristin Complex (mesylate) TP2285 Others QuinupristinDalfopristin Complex (mesylate) Quinupristin Dalfopristin Complex (mesylate) Quinupristin-Dalfopristin Complex inhibitor inhibit