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Plecanatide acetate

Catalog No. T12501 CAS 1075732-84-1

Plecanatide acetate is a agonist of guanylate cyclase-C (GC-C) receptor( EC50 of 190 nM in T84 cells), and shows anti-inflammatory activity in models of murine colitis.

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Plecanatide acetate, CAS 1075732-84-1

Pack Size	Availability	Price/USD
1 mg	35 days	$ 155.00
5 mg	35 days	$ 598.00
10 mg	35 days	$ 970.00
25 mg	35 days	$ 1,980.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	Plecanatide acetate is a agonist of guanylate cyclase-C (GC-C) receptor( EC50 of 190 nM in T84 cells), and shows anti-inflammatory activity in models of murine colitis.
Targets&IC50	GC-C (T84 cells):190 nM (EC50)
In vitro	Plecanatide acetate is a GC-C receptor agonist, binds and activates GC-C receptor(EC50 of 190 nM in T84 cells)[1].

Molecular Weight	1741.94
Formula	C67H108N18O28S4
CAS No.	1075732-84-1

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Shailubhai K, et al. Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis. World J Gastrointest Pharmacol Ther. 2015 Nov 6;6(4):213-22.

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Keywords

Plecanatide acetate 1075732-84-1 Others Plecanatide Acetate inhibitor inhibit

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