keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pepstatin Ammonium is a specific inhibitor of aspartic proteaseproduced by actinomycetes(hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM , respectively). Pepstatin Ammonium also inhibits HIV protease.
Description | Pepstatin Ammonium is a specific inhibitor of aspartic proteaseproduced by actinomycetes(hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM , respectively). Pepstatin Ammonium also inhibits HIV protease. |
Targets&IC50 | Hemoglobin-proctase:6.2 nM , Hemoglobin-acid protease:260 nM , Hemoglobin-pepsin:4.5 nM , Casein-pepsin:150 nM , Casein-acid protease:520 nM , Casein-proctase:290 nM |
In vitro | Pepstatin inhibits the recombinant HIV protease with an IC50 of 250 μM. |
In vivo | Pepstatin suppresses stomach ulceration of the pylorus in ligated Shay rats[1]. |
Synonyms | Pepstatin A Ammonium |
Molecular Weight | 702.92 |
Formula | C34H66N6O9 |
CAS No. | T12407 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 41.67 mg/mL (59.28 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Pepstatin Ammonium T12407 Others Pepstatin A Ammonium inhibitor inhibit